The All Layouts command of the Algorithms menu creates a block layout for the current project by executing all possible combinations of block layout algorithm settings. In other words its runs three side orientations times five improvement steps time two space allocation methods for a total of 30 algorithms. The block layout with the lowest shape adjusted distance score is retained and displayed at the conclusion. Because of its extensive computations this command may take a long time to complete. The Tiled space allocation method is especially computation time intensive, and its execution can be disabled with the Execute All Layouts dialog window, which is illustrated below. When you press Yes all possible combinations of layout algorithms will be executed for the current adjacency graph. If you press No, no algorithm will be executed.
For more information see:
Execute All Layout Algorithms Dialog Window
Execute All Layout Algorithms Data Items