Photo of Professor Lee

Eva K. Lee

Professor
Director, Center for Operations Research in Medicine and HealthCare
H. Milton Stewart School of Industrial and Systems Engineering
Georgia Institute of Technology
Atlanta, GA 30332-0205
Phone: (404) 894-4962
Fax: (404) 894-2301
Email: eva.lee AT gatech.edu
Co-Director, NSF I/UCRC Center for Health Organization Transformation

Distinguished Scholar in Health Systems, Health System Institute, Georgia Tech/Emory University


Personal Biosketch



Affiliations

Research Interests

  • Mathematical theory and modeling - complex/systems modeling, optimization and logistics theory, machine learning and predictive algorithms, decision theory and risk analysis.
  • High-performance computing - information technology, software enterprise design for industrial, biomedicine, and healthcare applications.
  • Large-scale optimization - linear/nonlinear mixed integer programming, combinatorial optimization, parallel algorithms.
  • Biomedicine and clinical research - biomedical modeling, informatics and algorithmic strategies for genomic analysis, health risk prediction, early disease prediction and diagnosis, optimal treatment strategies and drug delivery, healthcare outcome analysis and treatment prediction.
  • Healthcare policy, management, and decision analysis - systems modeling, quality improvement, operations efficiency, organizational transformation.
  • Public health and medical preparedness - emergency response, large-scale dispensing, disease propagation analysis, and economic impact.
  • Homeland security and defense - surveillance and detection, biodefense, radiological emergency preparedness, medical countermeasures, large-scale response and disaster relief logistics, population protection, design of resilient critical infrastructure.
  • Industrial applications - efficiency and quality of services; portfolio optimization, organizational transformation
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Refereed Articles, Proceedings, and Medical Abstracts(Selected)


MEDICAL THERAPEUTICS, QUALITY DELIVERY, SYSTEMS MODELING, OPTIMIZATION, AND DECISION MAKING

EK Lee, HY Atallah, MD Wright, ET Post, C Thomas IV, DT Wu, LL Haley. Transforming emergency department workflow and patient care. Interfaces - 2014 Franz Edelman Award Achievement in Operations Research 2015; to appear.
- Finalist, 2014 Franz Edelman Award Achievement in Operations Research

EK Lee, F Yuan, F Pietz, BA Benecke. Strategies for vaccine prioritization. Proceedings of the National Academy of Science 2014; submitted.

EK Lee, TW Lu, S Tal, J Jose. Medical alert management: An automated decision support tool to reduce alert fatigue. American Medical Informatics Association 2014; to appear.

EK Lee, CH Chen, F Pietz, B Benecke. An interactive web-based decision support system for regional medical dispensing, emergency preparedness, and bio surveillance. Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science 2014; submitted.

EK Lee, F Yuan, RL Zhou S Lahlou, E Post, M Wright, H Atallah, LL Haley. Modeling and optimizing emergency department workflow of large urban public hospital. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice Accepted 2013; to appear 2014.
- Second place, 2013 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, F Yuan, A Templeton, R Yao, K Kiel, JCH Chu. Biological planning for high-dose rate brachytherapy: Application to cervical cancer treatment. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2013; 43(5): 462-47.
- Finalist, 2012 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, F Pietz, B Benecke, J Mason, G Burel. Advancing public health and medical preparedness with operations research. Interfaces - The Franz Edelman Award Achievement in Operations Research 2013; 43(1): 79-98.
- Finalist, 2012 Franz Edelman Award Achievement in Operations Research.

EK Lee, F Yuan, D Hirsh, M Mallory, HK Simon. A clinical decision tool for predicting patient care characteristics: patients returning within 72 Hours in the emergency department. American Medical Informatics Association Annu Symp Proc 2012; 2012: 495-504.

CD Corley, R Arthur, RT Brigantic, C Bruckner-Lea, G Calapristi, JS Chung, G Dowling, D Hartley, S Kennedy, A Kircher, S Klucking, MJ Lancaster, T McKenzie, EK Lee, N Nelson, J Olsen, C Pancerella, T Quitugua, JT Reed, C Thomas, R Walters. Assessing the continuum of event-based bio surveillance through an operational lens. Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science 2012; 10(1):131-141.

EK Lee, CH Chen, N Brown, J Handy, A Desiderio, R Lopez, B Davis. Designing guest flow and operations logistics for the Dolphin Tales. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2012; 42(5): 492-506.
- Finalist, 2011 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

M Artzrouni, CB Begg, R Chabiniok, J Clairambault, AJE Foss, J Hargrove, EK Lee, JH Siggers, M Tindall. The first international workshop on the role and impact of mathematics in medicine: a collective account. American Journal of Translational Research 2011; 3(5):492-497.

BT Denton, O Alagoz, A Holder, EK Lee. Medical decision making: open research challenges. IIE Transactions on Healthcare Systems Engineering 2011; 1(3):161-167.

IOM (Institute of Medicine) and NRC (National Research Council), 2011. BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats. Abbreviated Version. Washington, DC: The National Academies Press. (The unabbreviated version is classified.)

EK Lee, A Mejia, T Senior, J Jose. Improving patient safety through medical alert management: an automated decision tool to reduce alert fatigue. American Medical Informatics Association Annu Symp Proc 2010; 417-421.

JJ Sturm, DA Hirsh, EK Lee, R Massey, B Weselman, HK Simon. Practice characteristics that influence nonurgent pediatric emergency department utilization. Academic Pediatrics 2010; 10(1): 70-74.

S Guerlain, EK Lee. Engineering the healthcare delivery system. Frontiers of Engineering: Reports on Leading-Edge Engineering from the 2009 Symposium (2010). National Academy of Engineering (NAE) (selected by NAE to organize and lead the "Engineering the Healthcare Delivery System" cluster)

EK Lee, CH Chen, F Pietz, B Benecke. Modeling and optimizing the public health infrastructure for emergency response. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2009; 39(5): 476-490.
-Finalist, 2008 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, HK Smalley, Y Zhang, F Pietz, B Benecke. Facility location and multi-modality mass dispensing strategies and emergency response for biodefense and infectious disease outbreaks. International Journal on Risk Assessment and Management - Biosecurity Assurance in a Threatening World: Challenges, Explorations, and Breakthroughs 2009; 12(2/3/4):311-351.

EK Lee. Mixed integer programming approach for cancer therapeutics. Paper for the 2009 National Science Foundation (NSF) Civil, Mechanical and Manufacturing Innovation Engineering Research and Innovation Conference. 1-9. Honolulu, Jun 2009.

EK Lee, M Zaider. Operations research advances cancer therapeutics. Interfaces -The Franz Edelman Award Achievement in Operations Research 2008; 38(1):5-25.
- Winner, 2007 Franz Edelman Award Achievement in Operations Research.

EK Lee. Optimization-based predictive models in medicine and biology. In: CJS Alves, PM Pardalos, LN Vicente, eds. Optimization in Medicine. Springer Optimization and Its Applications. The Netherlands: Springer 2008;12:127-151.

A Jayashankar, U Udayasankar, S Sebastian, M Kalra, EK Lee, W Small. MDCT of thoraco-abdominal trauma: an evaluation of the success and limitations of primary interpretation using multiplanar reformatted images versus axial images. Emergency Radiology 2008; 15(1):29-34.

PK Mehta, L Simpson, EK Lee, TA Lyle, ME McConnell, WM Book. Endothelin receptor antagonists improve exercise tolerance and oxygen saturations in patients with Eisenmenger syndrome and congenital heart defects. Texas Heart Institute Journal 2008; 35(3):256-261.

EK Lee. Large-scale optimization-based classification models in medicine and biology. Annals of Biomedical Engineering - Systems Biology, Bioinformatics, and Computational Biology 2007; 35(6):1095-1109.

EK Lee, TL Wu. Classification and disease prediction via mathematical programming. In: O Seref, OE Kundakcioglu, PM Pardalos, eds. Data Mining, Systems Analysis and Optimization in Biomedicine. AIP Conference Proceedings 2007; 953:1-42.

EK Lee, KD Cha, JO Deasy. Robust optimization to accommodate effects of systematic treatment uncertainties. In Proceedings for International Conference on The Use of Computers in Radiation Therapy 2007;6256:1-5. (Competitive selection, 5%)

EK Lee, KD Cha, T Bortfeld, JO Deasy. 4D-Image-Guided treatment planning optimization for managing organ motion in radiotherapy planning. Proceedings for International Conference on The Use of Computers in Radiation Therapy. 2007;6205:1-5. (Competitive selection, 5%)

EK Lee, T Easton, K Gupta. Novel evolutionary models and applications to sequence alignment problems. Annals of Operations Research - Computing and Optimization in Medicine and Life Sciences 2006; 148:167-187.

EK Lee, S Maheshwary, J Mason, W Glisson. Large-scale dispensing for emergency response to bioterrorism and infectious disease outbreak. Interfaces - OR Applications for Homeland Defense 2006; 36(6):591-607.

EK Lee, T Fox, I Crocker. Simultaneous beam geometry and intensity map optimization in intensity-modulated radiation therapy. International Journal of Radiation Oncology, Biology, Physics 2006; 64(1):301-320.

EK Lee, S Maheshwary, J Mason, W Glisson. Decision support system for mass dispensing of medications for infectious disease outbreaks and bioterrorist attacks. Annals of Operations Research- Computing and Optimization in Medicine and Life Sciences 2006; 148:25-53.

EK Lee, JO Deasy. Optimization in intensity-modulated radiation therapy. SIAG/OPT Views- and-News, Optimization in Medicine 2006; 17(2):20-32.

JO Deasy, EK Lee, T Bortfeld, M Langer, K Zakarian, J Alaly, Y Zhang, H Liu, R Mohan, R Ahuja, A Pollack, J Purdy, R Rardin. A collaboratory for radiation therapy treatment planning optimization research. Annals of Operations Research - Computing and Optimization in Medicine and Life Sciences 2006; 148:55-63.

EK Lee, S Maheshwary, J Mason, W Glisson. Decision support system for mass dispensing of medications for infectious disease outbreaks and bioterrorist attacks. Annals of Operations Research- Computing and Optimization in Medicine and Life Sciences 2006; 148:25-53.

EK Lee, S Maheshwary, J Mason. Real-time staff allocation for emergency treatment response of biologic threats and infectious disease outbreak.
- Winner, 2005 INFORMS William Pierskalla Best Paper Award on research excellence in HealthCare and Management Science.

L Simpson, EK Lee, BJ Hott, DJ Vega, WM Book. Long-term results of angioplasty vs stenting in cardiac transplant recipients with allograft vasculopathy. The Journal of Heart and Lung Transplantation 2005; 24(9):1211-1217.

L Simpson, PK Mehta, BJ Hott, JD Vega, EK Lee and WM Book. Long term results of angioplasty versus stenting In cardiac transplant recipients with allograft vasculopathy. International society for heart and lung transplantation (ISHLT) 2004. (Competitive selection, 2%)

EK Lee, M Zaider. Intraoperative dynamic dose optimization in permanent prostate implants. International Journal of Radiation Oncology, Biology, Physics 2003; 56(3):854-861.

EK Lee, T Fox, I Crocker. Integer programming applied to Intensity-modulated radiation therapy treatment planning. Annals of Operations Research - Optimization in Medicine 2003; 119:165-181.

EK Lee, M Zaider, Mixed integer programming approaches to treatment planning for brachytherapy - application to permanent prostate implants. Annals of Operations Research - Optimization in Medicine 2003; 119:147-163.

JC Landry, M Koshy, JD Lawson, N Esiashivilli, CA Staley, JY Ting, R Howell, S Ghavidel, EK Lee, LW Davis. Intensity modulated radiation therapy (IMRT) for retroperitoneal sarcoma: A case for dose escalation and organ at risk (OAR) toxicity reduction. Proceedings of American Society of Clinical Oncology 2003;22: 297. (Competitive selection, 1%)

EK Lee, J Deasy, M Langer, R Rardin, J Deye, F Mahoney. Final report - NCI/NSF workshop on operations research applied to radiation therapy, Washington, DC, February 7-9, 2002. Annals of Operations Research - Optimization in Medicine 2003; 119:143-146.

M Langer, EK Lee, JO Deasy, R Rardin, J Deye. Operations research applied to radiotherapy, an NCI-NSF - sponsored workshop February 7-9, 2002. International Journal of Radiation Oncology, Biology, Physics 2003; 57(3):762-768.

EK Lee, AYC Fung, JP Brooks, M Zaider. Automated tumor volume contouring in soft-tissue sarcoma adjuvant brachytherapy treatment. Physics in Medicine and Biology 2002; 47(11):1891- 1910.

EK Lee, M Zaider. On the determination of an effective planning volume for permanent prostate implants. International Journal of Radiation Oncology, Biology, Physics 2001; 49(4):1197-1206.

EK Lee, T Fox, I Crocker. Optimization of radiosurgery treatment planning via mixed integer programming. Medical Physics 2000; 27(5):995-1004.

M Zaider, M Zelefsky, EK Lee, K Zakian, HA Amols, J Dyke, J Koutcher. Treatment planning for prostate implants using magnetic-resonance spectroscopy imaging. International Journal of Radiation Oncology, Biology, Physics 2000; 47(4):1085-1096.

CS Wuu, RD Ennis, PB Schiff, EK Lee, M Zaider. Dosimetric and volumetric criteria for selecting source activity and a source type (125I or 103Pd) in the presence of irregular seed placement in permanent prostate implants. International Journal of Radiation Oncology, Biology, Physics 2000; 47(3):815-820.

EK Lee, RJ Gallagher, M Zaider, Planning implants of radionuclides for the treatment of prostate cancer: An application of mixed integer programmingOptima (Mathematical Programming Society Newsletter), feature article 1999; 61: 1-10.

EK Lee, R Gallagher, D Silvern, CS Wuu, M Zaider. Treatment planning for brachytherapy: an integer programming model, two computational approaches and experiments with permanent prostate implant planning. Physics in Medicine and Biology 1999; 44(1):145-165.

EK Lee, D Silvern, R Gallagher, LG Stabile, RD Ennis, CR Moorthy, M Zaider. Treatment planning for permanent prostate implants: genetic algorithm versus integer programming. Medical & Biological Engineering & Computing 1997; 35: Supplement Part 2. (Competitive selection, 4%)

RJ Gallagher, EK Lee. Mixed integer programming optimization models for brachytherapy treatment planning. Proceedings of the 1997 American Medical Informatics Association 1997;278-282. (Competitive selection, 5%)

< List of Selected Papers > < Top of Page >

BIOMEDICAL INFORMATICS, PREDICTIVE MODELS, EARLY DIAGNOSIS, OUTCOME PREDICTION

EK Lee, TW Lu, S Tal, J Jose. Medical alert management: An automated decision support tool to reduce alert fatigue. American Medical Informatics Association 2014; to appear.

MS Hagen, JK Jopling, TG Buchman, EK Lee. Priority queuing models for hospital intensive care units and the impacts to severe case patients. American Medical Informatics Association Annu Symp Proc 2013; 841-50.

C Koczor, EK Lee, R Torres, A Boyd, J. Vega, K Uppal, F Yuan, E Fields, A Samarel, W Lewis. Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computational analysis. Physiological Genomics 2013; 45(14):597-605.

C Koczor, R Torres, E Fields, A Boyd, S He, N Patel, EK Lee, A Samarel, W Lewis. Thymidine kinase and miDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation. Physiological Genomics 2013; 45(14):590-6.

EK Lee, TL Wu, F Goldstein, A Levey. Predictive model for early detection of mild cognitive impairment and Alzheimer's disease. Optimization and Data Analysis in Biomedical Informatics. Fields Institute Communications 2012; 63: 83-97.

JH Park, EK Lee, QY Wang, J Li, QF Lin, C Pu. Health-Connect: An Ontology-Based Model-Driven Information Integration Framework and Its Application to Integrating Clinical Databases. Proceedings of the 2012 IEEE 13th International Conference on Information Reuse and Integration (IEEE IRI 2012) 2012; 393-400.

EK Lee, F Yuan, D Hirsh, M Mallory, HK Simon. A clinical decision tool for predicting patient care characteristics: patients returning within 72 Hours in the emergency department. American Medical Informatics Association Annu Symp Proc 2012; 2012: 495-504.

R Eguchi, K Elwood, EK Lee. The 2010 Canterbury and the 2011 Christchurch New Zealand Earthquakes and the 2011 Tohoku Japan Earthquake: Emerging Research Needs and Opportunities Workshop Report. Earthquake Engineering Research Institute and the U.S. National Science Foundation 2012.

HI Nakaya, J Wrammert, EK Lee, et al. Systems biology of seasonal influenza vaccination in humans. Nature Immunology 2011; 12: 786-795.

EK Lee, HR Lee, A Quarshie. Seacoin-An investigative tool for biomedical informatics researchers. American Medical Informatics Association Annu Symp Proc 2011; 750-759.

EK Lee, A Mejia, T Senior, J Jose. Improving patient safety through medical alert management: an automated decision tool to reduce alert fatigue. American Medical Informatics Association Annu Symp Proc 2010; 417-421.

EK Lee, CH Chen, F Pietz, B Benecke. Disease propagation analysis and mitigation strategies for effective mass dispensing. American Medical Informatics Association Annu Symp Proc 2010; 427-431.

M Hagen, EK Lee. BIOSPIDA: A relational database translator for NCBI. American Medical Informatics Association Annu Symp Proc 2010; 422-426.

EK Lee, K Cha. Automated data collection and integration for cancer treatment design and clinical quality evaluation investigations. 2010 AMIA Summit on Clinical Research Informatics 2010. (Competitive selection, 7%)

JP Brooks, EK Lee. Analysis of the consistency of a mixed integer programming-based multi-category constrained discriminant model. Annals of Operations Research on Data Mining. 2010; 174(1): 147-168.

MT McCabe, EK Lee, PM Vertino. A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation. Cancer Research 2009; 69(1):282-291.

TD Querec, R Akondy, EK Lee, W Cao, HI Nakaya, D Teuwen, A Pirani, K Gernert, J Deng, B Marzolf, K Kennedy, H Wu, S Bennouna, H Olouch, J Miller, RZ Vencio, M Mulligan, A Aderem, R Ahmed, B Pulendran. Systems biology approach predicts the immunogenicity of the yellow fever vaccine in humans. Nature Immunology 2009; 10:116-125.
-Paper of the Year, 2011, by the International Society of Vaccines.

EK Lee. Machine learning framework for classification in medicine and biology. Integration of AI and OR Techniques in Constraint Programming for Combinatorial Optimization Problems. Lecture Notes in Computer Science 2009; 5547:1-7. (plenary speaker)

Q Ling, C Pu, EK Lee. A model-driven approach to manage clinical data in relational databases. IEEE Bioinformatics and Biomedicine, Workshop on Biomedical and Health Informatics 2008. (Competitive selection, 8%)

EK Lee. Optimization-based predictive models in medicine and biology. In: CJS Alves, PM Pardalos, LN Vicente, eds. Optimization in Medicine. Springer Optimization and Its Applications. The Netherlands: Springer 2008;12:127-151.

EK Lee. Large-scale optimization-based classification models in medicine and biology. Annals of Biomedical Engineering - Systems Biology, Bioinformatics, and Computational Biology 2007; 35(6):1095-1109.

EK Lee, TL Wu. Classification and disease prediction via mathematical programming. In: O Seref, OE Kundakcioglu, PM Pardalos, eds. Data Mining, Systems Analysis and Optimization in Biomedicine. AIP Conference Proceedings 2007; 953:1-42.

EK Lee, T Easton, K Gupta. Novel evolutionary models and applications to sequence alignment problems. Annals of Operations Research - Computing and Optimization in Medicine and Life Sciences 2006; 148:167-187.

FA Feltus, EK Lee, JF Costello, C Plass, PM Vertino. DNA motifs associated with aberrant CpG island methylation. Genomics 2006; 87:572-579.

EK Lee, R Gallagher, A Campbell, M Prausnitz. Prediction of ultrasound-mediated disruption of cell membranes using machine learning techniques and statistical analysis of acoustic spectra. IEEE Transactions on Biomedical Engineering 2004; 51(1):82-89.

FA Feltus, EK Lee, JF Costello, C Plass, PM Vertino. Predicting aberrant CpG island methylation. Proceedings of the National Academy of Sciences 2003; 100(21):12253-12258.

EK Lee, RJ Gallagher, D Patterson. A linear programming approach to discriminant analysis with a reserved judgment region. INFORMS Journal on Computing 2003; 15(1):23-41.

RJ Gallagher, EK Lee, D Patterson. Constrained discriminant analysis via 0/1 mixed integer programming. Annals of Operations Research - Non-Traditional Approaches to Statistical Classification and Regression 1997; 74:65-88.

RJ Gallagher, EK Lee, D Patterson. An optimization model for constrained discriminant analysis and numerical experiments with iris, thyroid, and heart disease datasets. Proceedings of the 1996 American Medical Informatics Association 1996; 209-213. (Competitive selection, 5%)

EK Lee, RJ Gallagher. Mixed integer programming models for machine learning and discriminant analysis, Proceedings of ICIAM 95.Zeitschrift fur angewandte Mathmematik und Mechanik.1996;76(3)491-492

< List of Selected Papers > < Top of Page >

LARGE-SCALE OPTIMIZATION (THEORY AND COMPUTATION) AND LOGISTICS

EK Lee, HY Atallah, MD Wright, ET Post, C Thomas IV, DT Wu, LL Haley. Transforming emergency department workflow and patient care. Interfaces - 2014 Franz Edelman Award Achievement in Operations Research 2015; to appear.
- Finalist, 2014 Franz Edelman Award Achievement in Operations Research

EK Lee, F Yuan, RL Zhou S Lahlou, E Post, M Wright, H Atallah, LL Haley. Modeling and optimizing emergency department workflow of large urban public hospital. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice Accepted 2013; to appear 2014.
- Second place, 2013 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

A Shapoval, EK Lee. Mixed integer programming convexification II, extension from posynomial to signomial functions. Mathematics of Operations Research 2013; submitted.

JP Brooks, EK Lee. Solving a mixed integer programming multi-category classification model with misclassification constraints. INFORMS Journal on Computing 2013; in press.

A Shapoval, EK Lee. Mixed integer programming, convexification of posynomial functions. Mathematics of Operations Research 2013; submitted.

EK Lee, Surana V, Shapoval A. Facets for generalized conflict hypergraphs. SIAM Journal on Optimization 2013; submitted.

EK Lee, S Maheshwary. Facets of conflict hyper graphs. SIAM Journal on Optimization 2013; submitted.

EK Lee, F Yuan, A Templeton, R Yao, K Kiel, JCH Chu. Biological planning for high-dose rate brachytherapy: Application to cervical cancer treatment. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2013; 43(5): 462-47.
- Finalist, 2012 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, F Pietz, B Benecke, J Mason, G Burel. Advancing public health and medical preparedness with operations research. Interfaces - The Franz Edelman Award Achievement in Operations Research 2013; 43(1): 79-98.
- Finalist, 2012 Franz Edelman Award Achievement in Operations Research.

EK Lee, CH Chen, N Brown, J Handy, A Desiderio, R Lopez, B Davis. Designing guest flow and operations logistics for the Dolphin Tales. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2012; 42(5): 492-506.
- Finalist, 2011 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, CH Chen, F Pietz, B Benecke. Disease propagation analysis and mitigation strategies for effective mass dispensing. American Medical Informatics Association Annu Symp Proc 2010; 427-431.

JP Brooks, EK Lee. Analysis of the consistency of a mixed integer programming-based multi-category constrained discriminant model. Annals of Operations Research on Data Mining. 2010; 174(1): 147-168.

EK Lee, CH Chen, F Pietz, B Benecke. Modeling and optimizing the public health infrastructure for emergency response. Interfaces - The Daniel H. Wagner Prize for Excellence in Operations Research Practice 2009; 39(5): 476-490.
-Finalist, 2008 INFORMS Daniel H. Wagner Prize for Excellence in Operations Research Practice.

EK Lee, HK Smalley, Y Zhang, F Pietz, B Benecke. Facility location and multi-modality mass dispensing strategies and emergency response for biodefense and infectious disease outbreaks. International Journal on Risk Assessment and Management - Biosecurity Assurance in a Threatening World: Challenges, Explorations, and Breakthroughs 2009; 12(2/3/4):311-351.

EK Lee, S Maheshwary, Facets of conflict hypergraphs. Annals of Operations Research - In Memory of Peter Hammer, Submitted 2008.

EK Lee. Modeling and optimization the public health infrastructure for emergency response. Modeling and Simulation for Emergency Management and Health Care Systems: Workshop Summary 2008.

EK Lee, M Zaider. Operations research advances cancer therapeutics. Interfaces - The Franz Edelman Award Achievement in Operations Research 2008; 38(1):5-25.
- Winner, 2007 Franz Edelman Award Achievement in Operations Research.

EK Lee. Optimization-based predictive models in medicine and biology. In: CJS Alves, PM Pardalos, LN Vicente, eds. Optimization in Medicine. Springer Optimization and Its Applications. The Netherlands: Springer 2008;12:127-151.

EK Lee. Large-scale optimization-based classification models in medicine and biology. Annals of Biomedical Engineering - Systems Biology, Bioinformatics, and Computational Biology 2007; 35(6):1095-1109.

EK Lee, TL Wu. Classification and disease prediction via mathematical programming. In: O Seref, OE Kundakcioglu, PM Pardalos, eds. Data Mining, Systems Analysis and Optimization in Biomedicine. AIP Conference Proceedings 2007; 953:1-42.

JP Brooks and EK Lee. Mixed integer programming constrained discrimination model for credit screening. In Proceedings of the 2007 Spring Simulation Multiconference, Business and Industry Symposium,1-6, Norfolk, VA, Mar 2007. ACM Digital Library.

JP Brooks and EK Lee. Solving a mixed-integer programming formulation of a multi-category constrained discrimination model. In Proceedings of the 2006 INFORMS Workshop on Artificial Intelligence and Data Mining1-6, 2006.

EK Lee, S Maheshwary, J Mason, W Glisson. Decision support system for mass dispensing of medications for infectious disease outbreaks and bioterrorist attacks. Annals of Operations Research- Computing and Optimization in Medicine and Life Sciences 2006; 148:25-53.

EK Lee, S Maheshwary, J Mason, W Glisson. Large-scale dispensing for emergency response to bioterrorism and infectious disease outbreak. Interfaces - OR Applications for Homeland Defense 2006; 36(6):591-607.

EK Lee, S Maheshwary, J Mason, Glisson, Emergency response decision support system for infectious disease outbreak and biodefense. Annals of Operations Research, Computing and Optimization in Medicine and Life Sciences 2006; 148: 25-53.

JCC Tsai, VCP Chen, EK Lee, EL Johnson, Parallelization of the MARS value function approximation in a decision-making framework for wastewater treatment. Computational Statistics and Data Analysis. COSMOS Technical Report 03-02 2005.(secondary link)

EK Lee. Generating cutting planes for mixed integer programming problems in a parallel computing environment. INFORMS Journal on Computing 2004; 16(1):3-26.

T Easton, K Hooker, EK Lee. Facets of the independent set polytope. Mathematical Programming B 2003; 98:177-199.

Bartholdi, J. J., III, D. Dave, EK. Lee. Computing optimal load plans in less-than-truckload freight networks. Advances in Manufacturing, Logistics, and Supply Chain Management: Proceedings of the International Workshop in IT-Enabled Manufacturing, Logistics, and Supply Chain Management 2003;1-22.

EK Lee, RJ Gallagher, D Patterson. A linear programming approach to discriminant analysis with a reserved judgment region. INFORMS Journal on Computing 2003; 15(1):23-41.

J Linderoth, EK Lee, M Savelsbergh. A parallel linear programming based heuristic for large scale set partitioning problems. INFORMS Journal on Computing 2001; 13:191-209.

EK Lee. A linear-programming based parallel cutting plane algorithm for mixed integer programming problems. Proceeding for the Third Scandinavian Workshop on Linear Programming 1999; 22-31.

RE Bixby, W Cook, A Cox, EK Lee. Computational experience with parallel mixed integer programming in a distributed environment. Annals of Operations Research - Parallel Optimization 1999; 90:19-43.

EK Lee, JE Mitchell. Computational experience of an interior-point SQP algorithm in a parallel branch-and-bound framework. Conference Proceedings High Performance Optimization I 1999; 329-347.

RE Bixby, EK Lee. Solving a truck dispatching scheduling problem using branch-and-cut. Operations Research 1998; 46(3):355-367.

EK Lee, J Mitchell. Computational experience of an interior-point algorithm in a parallel branch-and-cut framework. Proceedings for SIAM Conference on Parallel Processing for Scientific Computing 1997;1-9.

M Junger, EK Lee, P Mutzel, T Odenthal. A polyhedral approach to the multi-layer crossing minimization problem. Proceedings of the International Symposium on Graph Drawing. Lecture Notes in Computer Science, LNCS. Springer-Verlag 1997; 1353:13-24.

RJ Gallagher, EK Lee, D Patterson. Constrained discriminant analysis via 0/1 mixed integer programming. Annals of Operations Research - Non-Traditional Approaches to Statistical Classification and Regression 1997; 74:65-88.

EK Lee. On facets of knapsack equality polytopes. Journal of Optimization Theory and Applications 1997; 94(1):223-239.

EK Lee, J Mitchell. Computational experience in nonlinear mixed integer programming. The Operations Research Proceedings 1996;95-100.

< List of Selected Papers > < Top of Page >

REVIEWED BIOLOGICAL / MEDICAL ABSTRACTS

EK Lee, F Yuan, A Templeton, R Yao, K Kiel, JCH Chu. TCP-driven biological planning for high-dose rate brachytherapy. International Journal of Radiation Oncology Biology Physics 2013; 87(25): S415-2551.

EK Lee, F Yuan, A Templeton, R Yao, K Kiel, JCH Chu. SU-D-500-1:TCP-driven biological planning for high-dose rate brachytherapy. Medical Physics 2013;40(6):105.

EK Lee, F Pietz. SU-E-I-89: Real-time information and decision support for radiological emergency response. Medical Physics 2013; 40(6):146.

EK Lee, HJ Kang, D Cinalioglu, L Davis, G Frank. Systems modeling and simulation for reducing medication errors. Pediatric Academies 2013; 2910.103.

EK Lee, DA Hirsh, HK Simon. A clinical decision support tool for predicting patient readmission in the pediatric emergency department. Pediatric Academies 2012; 2938.598

EK Lee, F Yuan, R Yao, J Chu. PET-image TCP-driven biological planning for cervical cancer high-dose rate brachytherapy. Medical Physics 2011;38:3627.

EK Lee, KD Cha, JO Deasy and C Hamilton. Handling multiple clinical objectives in intensity modulated radiation therapy treatment planning. Medical Physics 2010; 37 (6):3214.

EK Lee, F Yuan, A Templeton, R Yao, JC Chu. PET-Image guided dose escalation in high-dose rate radiation therapy. International Journal of Radiation Oncology Biology Physics 2010;78(3):S415.

J Zhou, J Turian, EK Lee, A Templeton, Y Liao, J Chu, A novel approach to tracking intrafraction prostate motion during volumetric modulated arc therapy with tomosynthesis, Medical Physics 2010;37: 3386.

EK Lee, and KD Cha. Image-guided Adaptive Treatment Planning Optimization for IMRT. Medical Physics 2009; 236(6):2538.

EK Lee, KD Cha, and M Zaider. Automated Planning Volume Definition for HDR Brachytherapy:Application to Intraluminal Treatment of the Bile Duct. Medical Physics 2009; 36(6):2530.

EK Lee, and KD Cha. Image-guided Adaptive Treatment Planning Optimization for IMRT. Medical Physics 2009; 236(6):2538.

M McCabe, EK Lee, P Vertino. Multi-factorial prediction of aberrant CpG island methylation in cancer. AACR Special Conference Cancer Epigenetics 2008; A73.

EK Lee, KD Cha, JO Deasy. Robust optimization to accommodate effects of systematic treatment uncertainties. Medical Physics 2007; 34(6):2523-2524.

M McCabe, EK Lee, P Vertino. Predicting methylation-prone CpG islands in human cancer. Proc. Amer. Assn. Cancer Res 2007; 48:2839.

M McCabe, EK Lee, P Vertino. Multi-Factorial prediction of aberrant CpG island methylation in Cancer, The Sixth Georgia Tech - Oak Ridge International Conference on Bioinformatics - In silico Biology: Gene Discovery and Systems Genomics 2007;35.

EK Lee, KD Cha, JO Deasy. Robust optimization to accommodate effects of systematic treatment uncertainties. Proceedings for International Conference on The Use of Computers in Radiation Therapy 2007; 6256:1-5.

M McCabe, EK Lee, P Vertino. Multi-Factorial prediction of aberrant CpG island methylation in Cancer, The Sixth Georgia Tech - Oak Ridge International Conference on Bioinformatics - In silico Biology: Gene Discovery and Systems Genomics 2007;35.

EK Lee, KD Cha, T Bortfeld, JO Deasy. 4D-Image-Guided treatment planning optimization for managing organ motion in radiotherapy planning. Proceedings for International Conference on The Use of Computers in Radiation Therapy. 2007;6205:1-5. (Competitive selection, 5%)

EK Lee. Large-scale pattern recognition and classification approaches for disease diagnosis. Biomedical Engineering Systems Biology and Bioinformatics 2006.

EK Lee, M Zaider. Incorporating biological metabolite information within treatment of prostate carcinoma and analysis of dose escalation effect. International Journal of Radiation Oncology Biology Physics 2006; 66(3)(Suppl 1): S572-S573.

EK Lee, KD Cha, T Bortfeld, JO Deasy. 4D image-guided treatment planning optimization for managing respiratory effect in radiotherapy planning. Medical Physics 2006; 33(6) 2191-2192.

EK Lee, D Lewis, KD Cha. Efficient IMRT Delivery - Fast generation of integer-valued beam profiles. Medical Physics 2006; 33(6): 2096..

P Mehta, L Simpson, EK Lee, T Lyle, W Book. Endothelin-receptor antagonists improve exercise tolerance and oxygen saturations in adults with the Eisenmenger Syndrome. American Heart Association Scientific Sessions 3190 2005.

EK Lee, T Easton, K Gupta. Novel evolutionary models and applications to the sequence alignment problem. The Fifth Georgia Tech - Oak Ridge International Conference on Bioinformatics - Computational Genomics and Evolutionary Biology 2005;63.

EK Lee, FA Feltus, JF Costello, C Plass, PM Vertino. Large-scale genomic pattern recognition and classification of aberrantly hypermethylated CpG island loci in human cancer. The Fifth Georgia Tech - Oak Ridge International Conference on Bioinformatics - Computational Genomics and Evolutionary Biology,2005:62.

FA Feltus, EK Lee, JF Costello, C Plass, PM Vertino. DNA patterns associated with CpG island methylation state. The Fifth Georgia Tech - Oak Ridge International Conference on Bioinformatics - Computational Genomics and Evolutionary Biology 2005;50.

EK Lee, K Cha, T Bortfeld, JO Deasy. Multistage treatment planning optimization for managing organ motion in radiotherapy planning. International Journal of Radiation Oncology Biology Physics 2005;63(Suppl 1):S209-S210.

EK Lee, K Cha, T Bortfeld, JO Deasy. Multistage treatment planning optimization for managing organ motion in radiotherapy planning. Medical Physics 2005; 32(6):1925.

EK Lee, T Bortfeld, JO Deasy. Robust optimization including effects of systematic treatment errors. Medical Physics 2005; 32(6):1978.

EK Lee, D Lewis. Fast integer-valued smoothing of beam profiles in intensity modulated Radiation Therapy. Medical Physics 2005; 32(6):1974.

EK Lee, M Zaider. Incorporating biological metabolite information within treatment of prostate carcinoma. International Journal of Radiation Oncology, Biology and Physics 2004; 60(1):S370-371.

EK Lee, KD Cha, J Shi. Automated data collection and integration for cancer treatment design and clinical quality evaluation investigation. Joint BECON/BISTIC 2004 Symposium Biomedical Informatics for Clinical Decision Support: A Vision for the 21st Century 2004;P23.

EK Lee. Optimization techniques and their suitability and robustness for IMRT planning. 46th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2004; 31(6):1762.

EK Lee. Handling multiple clinical objectives in intensity modulated radiation therapy treatment planning. 46th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2004; 31(6):1777.

J Deasy, EK Lee, M Langer, T Bortfeld, Y Zhang, H Liu, R Mohan, R Ahuja, J Dempsey, A Pollack, J Rosenman, A Eisbruch, R Rardin, J Purdy, C Zakarian, J Alaly. An IMRT treatment planning research collaborator- 46th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2004; 31(6):1775.

M Koshy, JC Landry, JD Lawson, N Esiashivilli, CA Staley, JY Ting, R Howell, S Ghavidel, EK Lee, LW Davis. Potential for toxicity reduction using intensity modulated radiation therapy (IMRT) For retroperitoneal sarcoma. International Journal of Radiation Oncology, Biology, Physics 2003;57(2):S448-9.

JC Landry, M Koshy, JD Lawson, N Esiashivilli, CA Staley, JY Ting, R Howell, S Ghavidel, EK Lee, LW Davis. Intensity modulated radiation therapy (IMRT) for retroperitoneal sarcoma: A case for dose escalation and organ at risk (OAR) toxicity reduction. Proceedings of American Society of Clinical Oncology 2003;22: 297. (Competitive selection, 1%).

EK Lee, T Fox, I Crocker. Beam geometry and intensity map optimization in IMRT via computational optimization. 45th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2003; 30(6):1385-1386.

EK Lee, JO Deasy, I El Naqa, I Kawrakow, M Vicic. Integrating a Monte Carlo based optimization module into CERR for designing IMRT plans- 45th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2003; 30(6):1324.

M Koshy, JC Landry, JD Lawson, N Esiashivilli, CA Staley, JY Ting, R Howell, S Ghavidel, EK Lee, LW Davis. Intensity modulated radiation therapy (IMRT) for retroperitoneal sarcoma: A case for dose escalation and organ at risk (OAR) toxicity reduction. American Radium Society Houston, Texas. Cancer Journal Scientific American 2003;7(3-4):137-148.

EK Lee, R Wagman, M Zaider. Treatment planning with automated planning volume definition for HDR brachytherapy - Application to intraluminal treatment of the bile duct. International Conference on Translational Research and Pre-Clinical Strategies in Clinical Radio-Oncology - ICTR 2003 Advances In Translational Radiation Oncology: From Molecular Signalling to Cancer Cure 2003;36:2530.

EK Lee, M Zaider. Intraoperative dynamic dose optimization in permanent prostate implants. International Conference on Translational Research and Pre-Clinical Strategies in Clinical Radio- Oncology - ICTR 2003 Advances In Translational Radiation Oncology: From Molecular Signalling to Cancer Cure 2003;56(3)854-961.

FA Feltus, JF Costello, C Plass, EK Lee, PM Vertino. Identifying sequence patterns associated with aberrant CpG island methylation. Proceedings of American Association of Cancer Research LB:3 2002.

EK Lee, M Zaider. Intra-operative dynamic dose optimization for prostate permanent implants. 44th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2002; 29(6):1228.

EK Lee, T Fox, I Crocker. Mixed integer programming techniques applied to IMRT treatment planning optimization. 44th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2002; 29(6):1259.

JO Deasy, EK Lee, I Kawrakow, C Zakarian. A prototype Monte Carlo-based IMRT treatment planning research system. 44th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2002; 29(6):1254.

EK Lee, K Godette, C Anderson, J Keller. Effect of race and radiation treatment modalities on biochemical failure in prostate cancer cases. 44th American Association of Physicists in Medicine Annual Meeting. Medical Physics 2002;29(6).

EK Lee, AY Fung, M Zaider. Automated planning volume contouring in soft-tissue sarcoma adjuvant brachytherapy treatment. International Journal of Radiation Oncology, Biology, Physics 2001; 51(3): 391.

EK Lee, T Fox, I Crocker. Computational optimization for brain tumor radiosurgery treatment planning. 43rd American Association of Physicists in Medicine Annual Meeting, Salt Lake City Utah, July 2001. Medical Physics 2001; 28(6):1304.

EK Lee. An innovative computerized treatment planning system for permanent prostate implants. The American Association for the Advancement of Science 2001 Annual Meeting & Science Innovation Exposition, A41, February 2001. Invited presentation with media briefings

EK Lee, M Zaider. Intraoperative iterative treatment plan optimization for prostate permanent implants. 2nd International Innovative Solutions for Prostate Cancer Care meeting 2001; 32-33.

M Zaider, EK Lee. MRS-guided dose-escalation treatment planning optimization for permanent prostate implants. 2nd International Innovative Solutions for Prostate Cancer Care meeting 2001;36.

M Zaider, EK Lee, K Zakian, HA Amols, M Zelefsky, J Dyke, J Koutcher. Intensity-modulated conformal treatment planning for prostate implants using biological imaging. International Journal of Radiation Oncology, Biology and Physics 1999; 45(3):351.

EK Lee, M Zaider, M Zelefsky. On the definition of effective planning volume in permanent prostate implants. International Journal of Radiation Oncology, Biology and Physics 1999; 45(3):261-262.

EK Lee, D Silvern, R Gallagher, LG Stabile, RD Ennis, CR Moorthy, M Zaider. Treatment planning for permanent prostate implants: genetic algorithm versus integer programming. Medical & Biological Engineering & Computing 1997; 35: Supplement Part 2. (Competitive selection, 4%)

RE Bixby, W Cook, A Cox, EK Lee, Parallelism in mixed integer programming. Proceedings for the Center for Research on Parallel Computation Research symposium, 1994.

< List of Selected Papers > < Top of Page >

PUBLISHED BOOKS

Y Hui, EK Lee. Healthcare Data Analytics: Wiley Series in Operations Research and Management Science. Hoboken NJ: John Wiley & Sons, Inc 2015.

EK Lee. Operations Research for Medical Decision Making: Springer International Series in Operations Research and Management Science. The Netherlands: Springer Science 2014.

EK Lee, A Sofer, Computer Science Series. Computing and Optimization in Medicine and Life Sciences. The Netherlands: Springer Science 2012.

EK Lee, G Limo. Optimization in Medicine and Biology. Boca FL: Taylor and Francis Auerbach Publications 2008.

EK Lee, A Sofer, Computer Science Series. Computing and Optimization in Medicine and Life Sciences, Volume 2. The Netherlands: Springer Science 2006.

EK Lee, A Sofer. Computing and Optimization in Medicine and Life Sciences, Volume 1. The Netherlands: Springer Science, Kluwer Academic Publishers 2003.

REFEREED PUBLISHED BOOK CHAPTERS

EK Lee, F Yuan, RL Zhou, S Lahlou, E Post, MD Wright, HY Atallah, LL Haley Jr. Systems analytics: Modeling and optimizing emergency department workflow. In: Y Hui, EK Lee, eds. Healthcare Data Analytics. Wiley Series in Operations Research and Management Science. John Wiley & Sons, Inc. 2014.

EK Lee, F Pietz, B Benecke. Service networks for public health and medical preparedness: medical countermeasures dispensing and large-scale disaster relief efforts. In: JW Hermann, ed. Handbook of Operations Research for Homeland Security. The Netherlands: Springer 2013;183:167-196.(secondary link)

R Eguchi, K Elwood, EK Lee. The 2010 Canterbury and the 2011 Christchurch New Zealand Earthquakes and the 2011 Tohoku Japan Earthquake: Emerging Research Needs and Opportunities Workshop Report. Earthquake Engineering Research Institute and the U.S. National Science Foundation 2012.

EK Lee, AY Yang, F Pietz, B Benecke. Public health, emergency response, and medical preparedness I: Medical surge. In: JJ Cochran, ed. Wiley Encyclopedia of Operations Research and Management Science. Hoboken, NJ: Wiley 2011.(DOI: 10.1002/9780470400531.eorms1041)

EK Lee, F Pietz, B Benecke. Public health, emergency response, and medical preparedness II: Medical countermeasures dispensing and large-scale disaster relief efforts. In: JJ Cochran, ed. Wiley Encyclopedia of Operations Research and Management Science. Hoboken, NJ: Wiley 2011. (DOI: 10.1002/9780470400531.eorms1042)

EK Lee, AY Yang, T Guilford, F Pietz, B Benecke. Public health, emergency response, and medical preparedness III: Communication infrastructure. In: JJ Cochran, ed. Wiley Encyclopedia of Operations Research and Management Science. Hoboken, NJ: Wiley 2011. (DOI: 10.1002/9780470400531.eorms1043)

EK Lee, AY Yang, F Pietz, B Benecke. Public health, emergency response, and medical preparedness IV: Emergency evacuation. In: JJ Cochran, ed. Wiley Encyclopedia of Operations Research and Management Science. Hoboken, NJ: Wiley 2011.( DOI: 10.1002/9780470400531.eorms1046)

EK Lee, AY Yang, F Pietz, B Benecke. Public health and medical preparedness. In: Y Yih, ed. Handbook of Healthcare Delivery Systems. Boca Raton, FL: CRC Press, Taylor, Francis Group 2011:41-1:41-34.

EK Lee, K Gupta. Algorithms for genomics analysis. In: CA Floudas, PM Pardalos, eds. Encyclopedia of Optimization. 2nd. The Netherlands: Springer 2009;33-54.

EK Lee, TL Wu. Disease diagnosis: Optimization-based methods. In: CA Floudas, PM Pardalos, eds. Encyclopedia of Optimization. 2nd. The Netherlands: Springer 2009;753-784.

EK Lee, JE Mitchell. Integer programming: Branch-and-bound methods. In: CA Floudas, PM Pardalos, eds. Encyclopedia of Optimization. 2nd. The Netherlands: Springer 2009;1634-1643.

EK Lee, TL Wu. Classification and disease prediction via mathematical programming. In: PM Pardalos, HE Romeijn, eds. Handbook of Optimization in Medicine, Chapter 12. Springer Optimization and Its Applications. The Netherlands: Springer 2009;26:381-430.

EK Lee, K Gupta. Algorithms for genomics analysis. In: PM Pardalos, HE Romeijn, eds. Handbook of Optimization in Medicine, Chapter 9. Springer Optimization and Its Applications. The Netherlands: Springer 2009;26:291-323.

EK Lee, TL Wu, JP Brooks. Classification and disease prediction via mathematical programming. Classification and disease prediction via mathematical programming. In: GJ Lim, EK Lee, eds. Optimization in Medicine and Biology, Chapter 1. Boca Raton, FL: Auerbach Publications, Taylor, Francis Group 2008;3-60.

EK Lee, K Gupta. Algorithms for genomics analysis. In: GJ Lim, EK Lee, eds. Optimization in Medicine and Biology, Chapter 12. Boca Raton, FL: Auerbach Publications, Taylor, Francis Group 2008;355-393.

EK Lee, DP Lewis. Integer programming for telecommunications. In: MGC Resende, PM Pardalos, eds. Handbook of Optimization in Telecommunications, Chapter 3. The Netherlands: Springer 2006;67-102.

M Zaider, EK Lee. Treatment planning for low dose rate and high dose rate brachytherapy. In: AP Dicker, GS Merrick, FM Waterman, RK Valicenti, LG Gomella, eds. Basic and Advanced Techniques in Prostate Brachytherapy, Chapter 12. The United Kingdom: Taylor,Francis Group 2005;143-156.

EK Lee, M Zaider. Optimization and decision support in brachytherapy treatment planning.In: ML Brandeau, F Sainfort, WP Pierskalla, eds. Operations Research and Health Care: A Handbook of Methods and Applications, Chapter 28. International Series in Operations Research; Management Science, Vol 70. The Netherlands: Kluwer Academic Publishers 2004;722-740.

EK Lee. Branch-and-bound methods. In: PM Pardalos, MGC Resende, eds. Handbook of Applied Optimization, Chapter 3, Section 2. New York, NY: Oxford University Press USA 2002. (Honor- able mention by the Association of American Publishers- Outstanding Professional and Scholarly Titles of 2002 in Computer Science.)

EK Lee, JE Mitchell. Integer programming: Branch and bound methods. In: CA Floudas, PM Pardalos, eds. Encyclopedia of Optimization. The Netherlands: Kluwer Academic Publishers 2001;1049-1059.

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Courses

  • Spring 1996. (Columbia) IEOR 6608 Integer Programming
  • Spring 1997. (Columbia) IEOR 4600 Applied Integer Programming
  • Spring 1997. (Columbia) IEOR 4004 Introduction to Operations Research -- Deterministic Models
  • Fall 1997. ISyE 3231 Deterministic Operations Research
  • Winter 1998. ISyE 6662 Optimization II -- Part II:Integer Programming
  • Fall 1998. ISyE 3231 Deterministic Operations Research
  • Spring 2000 ISyE 4803 Topics in Optimization -- Applications to Real-World Problems
  • Spring 2001 ISyE 4104 Senior Design
  • Spring 2002. ISyE 6662 Optimization II
  • Fall 2002. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Cancer Bioinformatics and Computing
  • Spring 2003. ISyE 4231 Engineering Optimization (Section B)
  • Fall 2003. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Cancer Bioinformatics and Computing
  • Spring 2004. ISyE 4231 Engineering Optimization (Section C)
  • Fall 2004. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Large-Scale Biocomputing
  • Spring 2004. BIOL 8802 Topics in Bioinformatics -- Lectures on Cancer Bioinformatics and Predictive Models in Disease Diagnosis
  • Spring 2005. ISyE 4231 Engineering Optimization (Section C)
  • Fall 2005. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Large-Scale Biocomputing
  • Spring 2006. ISyE 4803/HS 8803 Operations Research in Medicine and HealthCare
  • Fall 2006. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Large-Scale Biocomputing
  • Spring 2007. ISyE 3133 Engineering Optimization (Section B)
  • Spring 2007. ISyE 4803/HS 8803 Operations Research in Medicine and HealthCare
  • Fall 2007. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Large-Scale Biocomputing
  • Spring 2008. ISyE 6679 Computational Methods
  • Spring 2008. ISyE 4601 Senior Design
  • Spring 2008 (Emory). BIOS 509 Biomedical Informatics in Clinical Research
  • Fall 2008. BIOL 8802/ISyE 8803 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Large-Scale Biocomputing
  • Spring 2009. ISyE 4803/8813/HS 8803 Operations Research in Medicine and HealthCare
  • Fall 2009. BIOL 8803/ISyE 8813/BIOL 4015 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Predictive Modeling
  • Spring 2010. ISyE 6679 Computational Methods
  • Spring 2010. ISyE 4803/8813/HS 8803 Operations Research in Medicine and HealthCare
  • Fall 2010. ISyE 6679 Computational Methods
  • Fall 2010. BIOL 7015/ISyE 8813/BIOL 4015 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Predictive Modeling
  • Spring 2011. ISyE 4803/8813/HS 8803 Operations Research in Medicine and HealthCare
  • Fall 2011. BIOL 7015/ISyE 8813/BIOL 4015 Cancer Biology and Biotechnology -- Lectures on Biomedical Informatics and Predictive Modeling

Hobbies

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